Searchable abstracts of presentations at key conferences in endocrinology

ea0029p3 | Adrenal cortex | ICEECE2012

The role of salivary cortisol measured by liquid chromatography-tandem mass spectrometry (LC-MS/MS) in the diagnosis of subclinical hypercortisolism (SH) in patients with adrenal incidentaloma (AI).

Palmieri S. , Morelli V. , Cairoli E. , Polledri E. , Fustinoni S. , Chiodini I. , Beck-Peccoz P.

Introduction: For defining SH in AI patients at least 2 altered criteria among serum cortisol after 1 mg dexamethasone test (1 mgDST), ACTH levels, 24 h urinary free cortisol (UFC) and midnight serum cortisol levels are generally required. Midnight salivary cortisol (MSC), a sensitive and easy-to-perform marker of overt hypercortisolism, appears to be of limited utility in these patients. Data on the role of salivary cortisol using LC-MS/MS, the gold standard procedure for ste...